About Hughes riskApps™

Kevin S. Hughes, MD

Co-Director of the Avon Comprehensive Breast Evaluation Center
Surgical Director, Breast Screening Program
Surgical Director, Breast and Ovarian Cancer Genetics and Risk Assessment Program
Massachusetts General Hospital
Boston, MA

Associate Professor of Surgery
Harvard Medical School

Dr. Hughes is a member of the Department of Surgical Oncology at the Massachusetts General Hospital where he is the Surgical Director of the Breast Screening Program, Surgical Director of the Breast and Ovarian Cancer Genetics and Risk Assessment Program, and Co-Director of the Avon Comprehensive Breast Evaluation Center.

He is a graduate of Dartmouth College and Medical School, and trained at Mercy Hospital of Pittsburgh in general surgery. He did a fellowship in surgical oncology at the National Cancer Institute. Dr. Hughes is an Associate Professor of Surgery at Harvard Medical School and was formerly on the faculty of Tufts University, the University of California, and Davis and Brown University. Dr. Hughes has served on numerous national and regional committees and is actively involved in research regarding the genetics, screening, diagnosis and treatment of breast cancer. He is the author of numerous papers and book chapters on the subjects of breast cancer, screening, diagnosis and treatment, and risk assessment.

Brian Drohan 

Brian has previously worked as an embedded systems programmer in the VOIP (Voice Over IP) industry prior to enrolling in a PhD program in the Biomedical Engineering department at the University of Massachusetts.  While completing his course work he has been actively involved in the academic collaboration with the Massachusetts General Hospital in developing methods for the population wide identification of patients at high risk for hereditary breast and ovarian cancer.  His current research interests are in visual analytics, mathematical modeling, and digital image processing.

Phil Bosinoff

Phil Bosinoff is a software consultant specializing in database applications, data mining, and advanced analytics, particularly applications and tools which require some level of mathematical modeling.  He is currently collaborating with others on the Hughes riskApps suite of cancer risk assessment tools.  Mr. Bosinoff has both undergraduate and graduate degrees in electrical engineering and computer science from MIT.  His career spans many years at IBM, ROLM, Tandem, Compaq, and Hewlett-Packard, where he developed several models and products for capacity planning, for computer performance, and for optimizing query execution times.  Mr. Bosinoff has several joint patents for data mining and analytic data analysis tools.  In addition to providing on-going consulting services for HP, Mr. Bosinoff also gets enjoyment tutoring college students in algebra, calculus, and statistics.


Mark Friendlich

Mark has a B.S. and M.S. in Computer Science from the University of Massachusetts. After graduation, he developed an AIX operating system monitor for BGS Systems. He also developed a multi-platform Unix system data collector, as well as a network data collector, for the BEST/1 for Unix capacity planning product. At Fidelity Investments, Mark was part of a small team that re-engineered a mission-critical middleware system. Based on this middleware, he created a number of services for connecting backend database systems with desktop applications and web frontends, which were used company-wide. Mark deployed these systems in a production environment. After leaving Fidelity, Mark developed and maintained networking protocols (SNA Gateway, CPI-C, LU6.2, DECnet, etc.) for Tru64 Unix, as well as Motif/X11 internals. Mark is an avid reader and nature lover. His other interests include poetry and music.


Chris Lawrence

Chris Lawrence is a software consultant specializing in the development of applications in the biomedical and pharmaceutical industries.  She began her involvement on the Hughes riskApps project in 2005 while she completed her Masters in Biomedical Engineering at the University of Massachusetts Lowell.  Ms. Lawrence obtained a BS in Computer Science from Worcester Polytechnic Institute.  In addition to her work on this project, Ms. Lawrence also works at Pfizer, developing software solutions to support drug discovery.  Her hobbies include sailing, travel and European board games.


Paulo G. Pastore, M.D.

Paulo Galluzzi Pastore is a graduate in Medicine at the Universidade de Santo Amaro, São Paulo, Brazil. Currently, he is on the second year of Pathology Residency Program in São Paulo, Brazil. He also has a degree in Social Sciences from the Universidade de Sāo Paulo, Brazil. He is collaborating with others on the Hughes riskApps on Snomed CT.


Fernanda C. G. Polubriaginof

Fernanda Polubriaginof is in her last year of Medical School at the Universidade de Santo Amaro, São Paulo, Brazil. She intends to apply for a Pathology Residency Program in the United States. She is keen on studying breast cancer and has collaborated on organizing international symposiums of breast cancer in São Paulo, Brazil. She is collaborating with others on the Hughes riskApps on Snomed CT.


Past Contributors

Jon Gersh

Jon Gersh began his career after graduating from Vanderbilt University back in the 80's.  He started by writing operating systems for some of the big Boston area computer manufacturers (Computervision, Wang) back in the day when you needed an operating system for every chip set.  Jon's first foray into healthcare software started with his move to Nashville's ENVOY Corporation, where he wrote one of the very first on-line pharmacy claims adjudication systems.  He helped author the standard for this with the National Council for Prescription Drug Programs, and built the network to do it (still predating the internet).  Back in Boston, Jon joined IDX Systems (later incorporated into GE Healthcare) and worked on the Web Framework, a familiar sight at hospitals throughout the country.  Later there he automated many Health Information Exchanges using standards to program master patient indexes and document repositories.  In his spare time, Jon is an avid banjo player, enjoys camping, motorcycles, and travel.


Sherwood S. Hughes

Sherwood was a software consultant specializing in the development of applications in the publishing, medical and telecommunications industries. He began his involvement on the Hughes riskApps project in 2002 and was the original developer. He is currently employed by the Massachusetts General Physicians Organization.


Brian G. Sweeney

Brian Gerard Sweeney graduated from Northeastern University, in Boston MA in 2009 with a Dual Bachelor of Science in Computer Science and Cognitive Psychology.  Brian’s studies included software development, computational theory, artificial intelligence, and theories of human cognition, just to name a few.
Brian began his technical career as an intern at TruSecure (now acquired by Verizon business) where he performed quality assurance tasks and load testing on their enterprise risk/compliance management software.

Brian next joined the Staples Middleware Services Delivery team where he configured and deployed an enterprise-wide monitoring system which provided centralized control and monitoring of business critical architecture.  While there he also deployed and configured an internal web server usage monitoring system comprised of open source software and custom scripts.

Brian’s next professional endeavor was with MITRE Corp. where he conducted a first order modeling/performance study of enterprise wide database replication architecture.
Brian’s last position was at Northeastern’s College of Computer and Information Science where he worked as a research assistant in the Relational Agents Group of the Human and Computer Interaction department.  There he worked on custom multithreaded servers which served content, in real time to experiment participants, provided database administration services for their experiment databases, built software installers for the distribution of experimental software and built custom experiment management applications for internal use by experiment administrators.  Brian was eventually awarded the undergraduate class of 2009 Outstanding Research Award by the College of Computer and Information Science for his work in the Relational Agents Group.

Brian currently works full time for Cipher Tech Solutions as a software engineer.  Here he enjoys supporting a wide variety of contracts ranging from digital forensics, to health care systems using technologies such as Java, and .NET.

In his free time he enjoys backcountry skiing, backpacking and blogging.


Our Mission

Hughes riskApps™ was originally conceived and developed by Kevin S. Hughes, MD and Sherwood S. Hughes of the Massachusetts General Hospital. The current product is the work of a consortium involving Massachusetts General Hospital, University of Massachusetts at Lowell, and the Newton-Wellesley Hospital.

Our mission is to create open source applications that help to identify risk in cancer patients.

The software is currently used in clinics and hospitals across the United States. Some of our clients include:

1. Massachusetts General Hospital

2. Newton Wellesley Hospital Breast Center

3. Brigham and Women's Hospital

4. Greater Baltimore Medical Center

5. Texas Health Presbyterian Dallas